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Biomechanics

Biomechanics is an interdisciplinary, multi-scale field of study in which the tools of mechanics are applied to biological systems. In practice, living tissues and their constituent components are highly mechanosensitive and mechanoresponsive. There is mounting evidence that even small forces, strains or shifts in material properties can drastically influence the behavior of systems of cells (i.e. substrate mechanical stiffness can control the differentiation state of stem cells). Thus, it is critical to develop tools capable of estimating to a high-degree of accuracy, the mechanical state of living biological systems. However, because of the complexity of the geometry and constitutive descriptions of tissues, cells and proteins, approaches to describe the mechanical response of these systems are challenging to devise, to apply and to validate. In the MIE department at Northeastern, we have a strong, talented group of researchers dedicated to biomechanics (and its corollary field: Mechanobiology). 

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